Once the design, including the technical arrangements, has been developed, its applicability can be tested in Dry Runs to ensure everything is properly working when the ‘real’ Trial is run, thus enabling to collect the required data in a proper way. For the execution phase, the methodology provides guidance for Dry Runs (steps 1 and 2) and running the Trial (step 3).
These subsequent steps are described in next sub-paragraphs. The execution phase results in sets of collected data. Acceptable data for the evaluation phase is acquired in an iterative manner by testing data quality assurance in a data collection plan and analyzability of data before and after the Dry Runs. This means that elements of the data collection plan are adjusted as more information about data quality is acquired.